Malvern Instruments has launched the Zetasizer APS, a dynamic light scattering system that automates size measurements of samples in 96- or 384-well microplates.
The Zetasizer APS is designed for protein specialists and is fully automated.
It allows quick investigation of a protein's condition at different stages of the purification process and at later stages of formulation under a range of environmental conditions.
In fully automating light scattering measurements using microwell plates, the Zetasizer APS makes screening and repeating sample measurements easy, and allows different types of measurement to be made on a single plate.
Once the auto level sensor has determined that there is sufficient sample in the well, the sample is transferred to a precision temperature and humidity controlled cell for measurement.
The sampling system and rinse protocol ensure no sample cross-contamination, something that is tested between every sample through a background measurement.
The sample is fully recoverable upon completion.
The Zetasizer APS has dual temperature control to separate the requirements of the measurement and of sample maintenance.
The programmable temperature control enables automated temperature trend measurements for melting point determination, protein purity or shelf-life investigations, for example.
The plate temperature is controlled separately to ensure samples are held under optimum conditions before measurement.
Software guides the development of standard operating procedures for repeatable measurement procedures and provides a range of result reports, as well as the ability to customise data output.
