Agilent Technologies has introduced the Agilent 6230 Accurate Mass time-of-flight (TOF) liquid chromatograph/mass spectrometer (LC/MS) system.
The instrument can detect and identify compounds in amounts smaller than two trillionths of a gram (2 picograms), making it a powerful tool for food safety, toxicology and other measurements where minute amounts of compounds must be identified.
Agilent has also compiled an extensive pesticide accurate-mass database, enabling users to identify pesticides in food and environmental samples with confidence.
The Agilent pesticide database contains accurate mass information for more than 1,600 compounds, including links to structural data found in Pubchem, Chemspider and other chemical databases.
The database also accommodates the addition of LC retention times which, combined with accurate mass results, provides increased confidence in confirming compound identity.
The pesticide database is the first of several planned accurate mass databases to complement the performance of Agilent Accurate Mass TOF and Q-TOF LC/MS instruments.
The company also plans to offer compound databases for toxicology and drugs of abuse.
The Agilent 6230 Accurate Mass TOF LC/MS delivers sub-1-ppm mass accuracy.
Mass resolution is enhanced with up to 20,000 resolving power at fastest spectral acquisition rates and up to 20 mass spectra per second, accommodating the latest high-throughput rapid-resolution liquid chromatography platforms.
Agilent Jet Stream thermal-gradient-focusing technology delivers on-column sensitivity gains of five times or more compared with previous instruments.
The proprietary design uses a sheath of super-heated nitrogen so that more ions and fewer solvent droplets enter the mass analyser.
The result is stronger signal and less noise than conventional designs for far greater sensitivity.
The Agilent 6230 Accurate Mass TOF uses Agilent Masshunter Workstation software with advanced data acquisition and qualitative and quantitative data-analysis capabilities.
These include data mining functionality based on molecular feature extraction and molecular formula generation algorithms, facilitating identification of compounds in complex mixtures.