Chemical imaging experts from Malvern Instruments will contribute two papers to the session on 'Chemical Imaging: Data Analysis and Emerging Techniques' at the IFPAC annual meeting.
Dr Janie Dubois, Malvern's product manager Americas for analytical imaging, will discuss 'Advanced troubleshooting of dissolution failure with chemical imaging', and Dr E Neil Lewis, technical director for Malvern, will make a presentation on 'Morphologically directed Raman microscopy: a novel approach for the characterisation of pharmaceutical products'.
Malvern said its Synirgi near infrared chemical imaging (NIR-CI) system is proving valuable for advanced troubleshooting of dissolution failure in both granules and tablets.
It provides accurate measurement of the spatial distribution of pharmaceutical ingredients.
Importantly, because chemical composition and structural data are obtained non-destructively, subsequent dissolution testing can be performed on the same sample.
This eliminates the need for destructive testing of different tablets from the same batch and removes any reliance on the statistical correlation of results.
