Human chorionic gonadotropin (hCG) is one of the most common analytes available for point-of-care (POC) pregnancy testing.
A publication in Clinical Chemistry entitled 'Quantitative, Wide-Range, Five-Minute Point-of-Care Immunoassay for Total Human Chorionic Gonadotropin in Whole Blood', by Piia von Lode et al uses Meridian Life Science (MLS) catalogue # MAF05-043, monoclonal antibody to beta hCG, clone # 057-10043 (OEM Concepts brand) in the development of a POC immunoassay for hCG.
This antibody is specific for intact-hCG and its beta subunit.
It does not cross react with hCG alpha subunit.
The authors developed a simple and rapid POC assay that relied on noncompetitive assay techniques similar to those in immunoassays used for routine laboratory testing.
Their POC assay reacted with hyperglycosylated hCG, nicked hCG, free hCGss, nicked free hCGss and hCGss core fragment.
