Agilent Technologies has announced its Sureprint G3 third-generation microarrays that contain up to one million probes on a standard 1in x 3in glass slide.
Initial applications are array-based comparative genomic hybridisation (aCGH) and copy number variation (CNV), with other applications to follow.
'The Sureprint G3 microarrays will address customers' needs for higher resolution CGH/CNV data while providing a lower cost per data point,' said Chris Grimley, Agilent senior marketing director, genomics.
Sureprint G3 microarrays for CGH/CNV are available in four standard formats: a single million-feature array per slide (1x1M), and several multipack formats - 2x400K, 4x180K, and 8x60K.
Agilent offers a catalogue CGH microarray for each format as well as the four custom formats.
Providing multiple arrays per slide reduces cost per experiment, enabling researchers to perform larger sample studies with the same budget.
By using Agilent's Earray online tool to design custom arrays, researchers can choose from more than 24 million predesigned, in silico-validated aCGH probes, spanning non-repeat regions of the genome.
Earray allows customers to use the flexibility of the Agilent Sureprint ink jet microarray fabrication platform.
Custom arrays from Agilent are available at no additional cost to the user.
As part of the new portfolio of catalogue products, Agilent is introducing a 2x400K CNV catalogue array, which is designed to cover the known CNV regions from the Database of Genomic Variants.
This is the first of several CNV-focused arrays that Agilent will be releasing in 2009.
The catalogue arrays are comprehensive whole-genome arrays that provide high-density coverage of coding and non-coding regions, emphasising known genes, promoters, MiRNAs, CNVs, disease regions, pseudoautosomal and telomeric regions.