Caliper Life Sciences has launched the Staccato protein workstation to specifically address bottlenecks in the characterisation of biological therapeutics and biogenerics.
With a goal of assuring the quality of therapeutic proteins and monoclonal antibodies, as well as creating mechanisms for approval of follow-on protein products (biosimilars), the FDA has encouraged the industry to submit biological new drug applications that include quality-by-design parameters.
The quality by design approach requires multivariate experimentation techniques that generate large numbers of samples and create bottlenecks in sample preparation and analysis.
The Staccato protein workstation incorporates the Sciclone ALH 3000 for automated liquid handling, Twister II for microplate handling, Labchip GXII for microfluidic protein characterisation, and various accessories for complete workflow automation.
The Labchip GXII is Caliper's high-throughput system for analysing protein size, concentration, and purity and serves as a replacement for traditional polyacrylamide gel electrophoresis.
