The IL-1 isolated lung perfusion system from Hugo Sachs Elektronik and Harvard Apparatus is a complete respiratory physiology workstation for the isolated lungs of mice.
The core of the system is the patented perfusion architecture that allows both a positive and negative pressure ventilation capability in the same compact unit.
The 'reclining lung' position in the IL-1 simplifies organ preparation in delicate mouse lungs as the surgery takes place directly in the completely sealed water-jacketed lung chamber.
The chamber also serves as an artificial thorax during negative pressure ventilation.
The included transducers and probes measure airflow, tidal volume, dynamic resistance and compliance, as well as arterial and venous pressure and flow.
Blood gas parameters such as pH, pO2 and pCO2 are continuously measured in real time.
All respiratory and vascular parameters are measured and calculated using the included software.
The IL-1 isolated lung perfusion system provides every necessary component to simplify and increase the efficiency of ex-vivo respiratory physiology assays in sensitive mouse models.
