Rapid Particle Systems has announced that its Layer Explorer is being used by manufacturers to determine the distribution and thickness of silicon layers in parenteral primary packaging.
Using Layer Explorer, manufacturers and fillers of products for the pharmaceutical industry are able to determine, with nanometre precision, the distribution and thickness of silicon layers in parenteral primary packaging, such as cartridges, carpules and vials, without destroying or interfering with the syringe or silicon layer.
A leading manufacturer of prefilled syringes relies on Layer Explorer for the quick optical characterisation of silicone oil layers, even in the development of its pharmaceutical packaging.
Prefilled syringes are modern yet complex application systems that have been playing an increasingly important role in the fields of pharmaceuticals and biotechnology.
Knowing the siliconisation profile of each individual nozzle in a production line allows manufacturers and users to quickly and accurately determine and apply better parameters.
The quality and chemical characteristics of the analysed packaging are documented for the customer in a reproducible and comparable manner.
A leading vaccine manufacturer also uses Layer Explorer to measure the homogeneity and amount of silicone oil prior to filling its vaccines, in order to prevent syringe plungers from sticking during vaccination.
This is said to help to prevent the malfunctioning of individual syringes or even recalling entire batches.
Layer Explorer allows manufacturers of monoclonal antibody solutions, for example, to analyse the silicone layer even after filling without wasting any of their products.
The technology is also claimed to benefit plant manufacturers.
A leading equipment supplier for pharmaceutical filling lines uses Layer Explorer to optimise the parameters for the siliconisation stations of its manufacturing machines and to quickly achieve high-quality and measurable siliconisation results.