The Tru Block is a highly potent reagent that actively blocks the heterophilic antibody (HA) interference in immunoassays, including Human Anti-Mouse Antibody (HAMA) interference.
According to the company, Tru Block offers advantages over traditional Mouse IgG reagents that inhibit HAMA by serving as antigens of HAMA.
Tru Block works differently, using a proprietary active mechanism, and is said to be five to 20 times more effective than Mouse IgG on HAMA blocking, reducing blocker usage.
Tru Block works well on HAMA as well as other types of HA, while Mouse IgG is effective only on HAMA.
Extensive quality control (including a HAMA blocking functional assay, purity and bioburden testing) ensures that every batch of Tru Block is well characterised.
Guaranteed as greater than 95 per cent pure the Tru Block delivers consistent performance.
Lot-to-lot consistency further reduces the need for adjusting assay reagents to optimise performance.