Comet Assay IV from Perceptive Instruments has a scoring method that has been validated in-house and by a range of pharmaceutical organisations and CROs.
As part of the JaCVAM initiative to validate the in-vivo and in-vitro comet assays, Comet Assay IV is used by laboratories in Japan, Europe and the US.
The aim of the initiative is to work towards the introduction of an OECD guideline for the assay.
As an ISO9001:2008 approved company, Perceptive develops and tests its software in accordance with strict quality guidelines.
The company's in-house validation exercises were performed on real and artificially generated comet images.
Every attribute of each generated image was known in advance so the accuracy of any measurements obtained could be verified exactly.
Comet Assay IV's single-click scoring system enables users to score 50 cells within 2min.
