Intelligent structured illumination microscopy from Leica Microsystems uses the Optigrid technique to produce ultra-sharp images.
Used with Leica's quality optics, the aperture diaphragm integrated with the fluorescence light path also enhances contrast.
The automatic-focus function of the Optigrid keeps the grid structure in focus, from UV to IR light.
A feature of this development is that the same Optigrid module can be used both for upright and for inverted Leica research microscopes.
There is no need to change the grid, as one optimised grid covers all magnifications from 10x to 100x.
The Optigrid module integrated with Leica research microscopes is controlled by Leica MM AF software and complemented by a wide selection of fluorescence cameras.