The Fill-It benchtop dispensing system is being used at a biological resource centre to improve filling precision and reduce the time required to dispense cells into large numbers of cryovials.
Scientists at the cell-culture centre have used Fill-It since 2008 to dispense frozen cells in a consistent volume into stock cryovial for cell-banking and assay-ready drug-discovery applications.
They chose Fill-It because their validation studies showed that it is the most efficient way to uncap, dispense cells and recap a large batch of screw-cap 24 Nunc cryovials, while still maintaining aseptic conditions.
'In the 18 months we have been using Fill-It, we have tested it with around 20 different recombinant and non-recombinant cell types, including CHO, HEK293 and some neuronal cell lines, and all the cells grow well after automated dispensing,' said a project manager at the cell-culture centre.
'The system can improve accuracy of dispensing without compromising the growth and utility of the cell lines, and means any pharma company or biological resource institute can confidently install a Fill-It to reduce the time and costs associated with producing large cell banks or with dispensing cells for major drug-discovery projects,' added Stephen Guy, technology group manager at TAP.