GE Healthcare's Biacore T200 soystem is designed to offer high sensitivity in the measurement of kinetic, affinity, concentration, specificity and thermodynamic interaction data in real time.
Biacore T200 enables analysis of interactions involving the smallest, low molecular weight compounds, interactions of rare targets, and facilitates the analysis of interactions involving G protein-coupled receptors.
The high sensitivity of the system also allows antigen immobilisation levels so low that interactions with antibody in solution can be analysed without avidity effects, said GE.
The system is also said to expand the range of kinetic parameters that can be studied with the highest precision, from the fastest on rates to the slowest off rates.
Guided workflows and the ability to analyse up to 384 samples in unattended runs facilitates rapid data acquisition for a large range of biomolecular interaction studies, including defining potential drug targets and diagnostic markers, as well as time- and cost-efficient concentration analysis in vaccine development.
Calibration-free concentration analysis enables reproducible, precise measurement of active protein concentration, whether or not a standard is available.
Biacore T200 also provides dedicated support for immunogenicity testing, for detection and characterisation of anti-drug antibodies during pre-clinical and clinical development.
The optional GxP Package enables Biacore T200 to integrate into GxP-regulated workflows.
