Perceptive Instruments has announced that its Comet Assay IV software has been used to score a variety of comet assay slides.
First, the comet assay scoring software has been used for investigations into Xanthohumol, a hop-derived prenylated flavonoid found in beer.
Investigations suggest that it protects against DNA damage induced by a common cooked food mutagen in rat colon mucosa and liver cells.
Second, the software has been used in a small clinical study in healthy adult volunteers who demonstrated that drinking green breakfast tea reduces the genotoxic effects induced by artificial exposure to UVA/VIS radiation in peripheral blood cells.
Another study investigating the protective properties of Glucomannan has also generated some interesting results, according to the company.
The research suggests that the commonly used thickener and emulsifier has some protective effects on faecal water-induced DNA damage on Caco-2 cells, which are further enhanced by partial hydrolysis.
Research scientists use Comet Assay IV to provide reliable, reproducible and accurate measurements.
