Biofocus, a provider of integrated gene-to-clinical candidate drug discovery services, has announced the launch of two compound libraries targeting Family C GPCRs and protein-protein interactions.
The company's new protein-protein interaction library (PPI01) is designed around a scaffold that mimics a 'beta-sheet type' hydrogen bonding pattern, a key motif observed in protein-protein interactions.
The new Fieldfocus GPCR Library (FFG01) is designed using field- and shape-based overlays of known ligands to generate a novel library that targets the allosteric site of metabotropic glutamate receptors, a subtype of Family C GPCRs.