Advanced Biomatrix has launched a 3D matrix cell adhesion product, Type IV, Human Collagen, for culturing epithelial, endothelial, muscle, nerve and many other cell types.
Collagen IV is the primary collagen found in the extracellular basement membranes separating a variety of epithelial and endothelial cells.
It is a major component of the dermal-epidermal junction where it is mostly found in the lamina densa.
It is a heterotrimeric molecule containing two a1-like and one a2-like genes.
The Type IV, Human Collagen is isolated from human placenta and is purified using a multi-step process.
The product is supplied as a sterile, lyophilised powder containing 5mg of Type IV collagen per vial.
Type IV human collagen is typically used as a thin coating on tissue culture surfaces.
This product is used in vitro as a substrate scaffold to enhance cell attachment, adherence and proliferation.