Integenx has used the Cavro mini sample processor (MSP) 9250 from Tecan as the basis for an automated Sanger sequencing sample preparation platform.
The Apollo 100 Sanger sequencing automation system uses the Cavro MSP 9250 to automate bulk liquid transfers, interfacing directly with Intergenx's MOVe microfluidic technology to enable users to work with small volumes, from 10 nanolitres to 100 microlitres.
James Nelson, marketing director at Integenx, said: 'With Sanger sequencing, the major "pain point" for the researcher is the expense of both the Big Dye and clean-up reagents.
'The process is relatively expensive when performed manually, but, once automated with a microfluidics chip, the reagent volumes used can be dramatically reduced, meaning that the initial cost of automation pays for itself through the reagent cost savings generated.
'Sample volumes for manual methods are typically in millilitres, and the Apollo 100 system provides an easy-to-use interface between the "macro world" and our microfluidic technology that handles microlitre to nanolitre volumes.
'To transfer samples from macro to micro we required a robotic system that was highly reliable and robust.
'Tecan was a name our customers knew and trusted, and the Cavro MSP matched our needs really well.
'We are now planning to incorporate Tecan's robotic liquid handlers into future products based on our MOVe technology, including solutions in the field of next-generation sequencing,' Nelson added.
