Biodiscovery has announced the release of version 5.1 of its Nexus Copy Number software, a platform-independent application for DNA copy number analysis.
Version 5.1 offers improvements in the user interface that allow for detailed information about a sample and functions to enable efficient review of samples, identification of possible pathogenic regions, compare with already processed samples, obtain annotations from many external databases and generate customised reports.
A number of improvements to processing include the Fasst2 segmentation algorithm, incorporation of PennCNV processing and support for Affymetrix Oncoscan (MIP technology) arrays.
With new preprocessing steps, the software can adjust for samples with aneuploidy and correct for any systematic biases (such as GC wave patterns), even samples with a lot of artifacts can be salvaged to extract high-quality data for reliable results.
'Increasing numbers of users are utilising Nexus Copy Number not just as an analysis tool for individuals but as a platform for large-scale studies involving the sharing of data across the globe, harnessing the power of Nexus DB, the web-based repository linked with Nexus Copy Number,' said Soheil Shams, president of Biodiscovery.
Nexus Copy Number can integrate and process together, in a single project, data from commercial array platforms such as Agilent, Affymetrix, Illumina, Roche Nimblegen, Next Gen read depth, as well as custom arrays.
Nexus Copy Number offers free access to a web-based repository for querying and storing genomic data from any location.
The software is applicable to many types of studies from focused projects of a cytogeneticist to large-scale cancer or GWAS studies.
Biodiscovery offers the product as a flexible and modular system to allow users to create configurations suited to their needs.
