Malvern Instruments diffraction specialist Dr Anne Virden has published an article providing guidance on how to develop a robust method for laser diffraction particle size analysis.
Highlighting information included in the latest release of ISO13320 (the international standard relating to laser diffraction), the author emphasises the importance of considering the whole analytical procedure - from sampling through to measurement - for successful method definition.
For many analysts, routine laser diffraction particle size analysis simply involves loading the sample and pushing a button to begin measurement.
Reaching this desirable endpoint requires the definition of a reliable and reproducible method, which can be automated through the use of standard operating procedures and appropriate software.
Sampling, sample preparation and dispersion, plus measurement conditions can all impact the data obtained and must therefore be rigorously and systematically considered.
For those unfamiliar with laser diffraction, this can sometimes appear to be the biggest hurdle to employing the technique.
The latest version of ISO13320 reflects this and includes a substantial amount of advice.
Virden's paper, 'Method development for laser diffraction particle size analysis', is currently available for download.
