Amsbio has introduced Geneporter Gold, a highly efficient and reproducible lipid-based reagent for effective transfection of a variety of cell lines.
Molecular target delivery faces many barriers, from crossing the cell type-specific extracellular membrane, to cytoplasmic degradation and translocation across the nuclear membrane.
To be effective, the transfection reagent/DNA complexes must overcome all of these challenges while minimising cytotoxicity.
Traditionally, the most efficient delivery methods have also been the most cytotoxic.
Using Advanced Carrier Enhancement technology, a nuclear targeting mechanism that maximises transfection and transgene expression levels while still maintaining high cell viability, Geneporter Gold has been able to address this limitation.
Geneporter Gold is said to combine consistent delivery and reliability with the lowest reported cytotoxicity of commercially available transfection reagents.
The Geneporter Gold protocol has been optimised to provide simple, same-day transfection, making it suitable for high-throughput or large-scale applications where the need for consistent results is desirable.
