Fluidigm has introduced the Biomark HD Real-time PCR System, which it claims is the company's most advanced instrument for genomic analysis ever.
The Biomark HD System is designed for researchers who require the sensitivity and throughput needed to study gene expression down to the single-cell level - especially those who have limited amounts of sample or study rare populations of cells.
In addition to the throughput advances, the BioMark HD System features a number of important design changes incorporated to improve performance, lower operating costs and provide an expanded applications suite.
The Biomark HD System relies on the same Fluidigm nanofluidic technology that delivers savings in cost and time by providing massive parallelism of experiments and an easy-to-use workflow.
By incorporating a new fast thermal-cycling protocol, the Biomark HD System reduces time to result by increasing the throughput of the original system twofold.
Users now have the ability to generate over 50,000 data points in one day with only one technician.
The fast thermal-cycling protocol is compatible with commercially available assays and yields data that is equal in quality to standard cycling protocol data.
The Biomark HD platform continues to support all the applications of the original Biomark System, including gene expression, single-cell gene expression and genotyping.
Using Digital Array chips, the system performs common digital PCR applications, such as mutation detection, copy number variation and absolute quantitation of nucleic acid sequences.