Molecular Profiles has expanded its manufacturing capabilities with the purchase of the Xcelodose 120S system, a precision powder micro-doser that speeds drug development for customers.
Xcelodose is a precision powder micro-doser that can accurately fill capsules or vials with just the drug material alone and therefore requires no initial formulation development, allowing rapid progress to the clinic.
As a result, the company said customers can benefit from a shorter drug-development process by reducing the need for expensive and time-consuming stability studies.
This in turn reduces the time taken to reach the 'first in human' clinical trial decision point, which facilitates an increase in throughput of candidate compounds for development.
The system also offers highly consistent dose accuracy and operates with generation of very little waste, the company added.
The Xcelodose provides the capability to dose quantities as small as 100ug into capsules or vials, which is not possible by manual weighing.
The system can be easily contained to prevent operator exposure.
This is valuable for supporting the development of drugs that are highly potent and toxic, such as oncology drugs.
