Agilent Technologies has introduced its Intelligent System Emulation Technology (ISET), which is claimed to accelerate and facilitate inter-laboratory LC method transfer.
The technology harnesses the power and accuracy of the Agilent 1290 Infinity LC to emulate other systems for the transfer of methods between LCs, regardless of brand.
It is claimed to make the 1290 Infinity LC the first universal LC system as it can execute other HPLC and UHPLC methods and deliver the same chromatographic results without any change of the instrument or the original method.
The 1290 Infinity LC, together with ISET, allows the user to: emulate other (U)HPLC instruments by a simple mouse click; run existing (U)HPLC methods without modifying the method or system; and deliver the same retention times and peak resolution for better method transfer.
QA/QC laboratories can now run their legacy methods unchanged and take full advantage of the UHPLC speed, resolution and sensitivity of the 1290 Infinity LC.
Method development labs are able to speed up their method development with UHPLC performance and then fine-tune the new method by emulating the target system.
'Instrument-to-instrument method transfer is often problematic, especially in highly regulated industries, because any modifications of the instrument and original method should be avoided,' said Christian Gotenfels, 1290 Infinity LC product manager for Agilent Technologies.
Stefan Schuette, senior marketing director of Agilent's Liquid Phase Separations business, added: 'The 1290 Infinity LC with ISET, however, is poised to revolutionise LC method transfer because it minimises the cost for development, validation and execution of (U)HPLC methods while eliminating redevelopment and revalidation costs.
'Development laboratories, QA/QC departments and contract research and manufacturing organisations will be free to develop, validate and execute all methods on one single instrument, as the 1290 Infinity LC with ISET will be able to emulate those HPLC and UHPLC instruments to which a method should be transferred or on which it has been developed,' he said.
The 1290 Infinity LC with ISET will be available to order in the third quarter of 2011.
Existing 1290 Infinity LC systems are fully compatible and upgradable to ISET.