Chimermarker integrates the previously distinct analysis operations for initial donor/recipient compatibility and post-engraftment longitudinal studies.
The software, compatible with outputs from all major capillary electrophoresis platforms as well as commercially available STR and custom chemistries, integrates sizing, allele calling with automated Chimerism analysis, eliminating the need for tedious and error-prone data transfer.
Chimermarker software can be used to monitor Chimerism in allogeneic and autologous stem-cell transplant, hematopoietic stem-cell transplant, bone-marrow transplant and peripheral blood-stem cell transplant.
The program preferences include labelling of peak ratios by height or area, with multi-lineage capabilities for Chimerism analysis of T-cells, B-Cells and other cell-type populations, which may indicate graft-versus-host disease or graft rejection.
Case-specific panels are automatically constructed using donor recipient allele calls.
The software package includes a user management audit trail function, which protects the analysis parameters results and edits and ensures use only by authorised personnel.
