Sigma Life Science has announced the availability of over 10,000 Mission 3' UTR Lenti Go Clones, powered by Switchgear Genomics, for straightforward microRNA (miRNA) target validation.
This novel target-reporter system combines Switchgear Genomics' reporter assay expertise with Sigma Life Science's patented lentiviral technology to provide ready-to-use vectors that can enable scientists to understand gene regulation in a variety of cell types, including primary cells.
The library is available through Sigma Life Science's fully searchable Your Favorite Gene powered by Ingenuity (YFG) web portal.
Switchgear Genomics' Go Clone miRNA target sets are already widely used for investigation of gene regulation by micro RNAs.
The availability of these reporter vectors in Sigma's lentiviral format can provide stable transfection into a range of cell types - including difficult-to-transfect lines such as primary cells and stem cells - without the need for time-consuming and laborious reporter cloning.
