Biotage has introduced the Biotage Initiator Peptide Workstation for manual microwave-assisted peptide synthesis.
The workstation utilises a microwave peptide vial available in two sizes; 2-5ml for 75-150umol-scale or 10-20ml for 250-500umol-scale synthesis.
Biotage claims to be the only manufacturer of traditional, room-temperature peptide synthesisers, as well as microwave peptide synthesisers in both entry-level and high throughput configurations.
The Initiator Peptide Workstation enables simple workflow for microwave-assisted peptide synthesis in a Biotage Initiator microwave synthesiser without system modifications.
Synthesis is performed directly in the specially designed microwave vial, then filtered and washed using the wash station.
Material can be collected in a standard GL 45 laboratory glass bottle, 50ml centrifuge tube or a round-bottom flask.
The workstation is a versatile solution for both microwave-assisted solution and solid-phase peptide synthesis.
It is also cost-effective system, delivering a high level of control for close monitoring of the quantity of reagents used, resulting in minimised waste and reduced cost.
The workstation provides a solution for performing various types of chemistry using microwave irradiation under atmospheric conditions at temperatures up to 100C, including: solution and solid phase synthesis, organic, peptide (Fmoc and Boc), peptoid and PNA (peptide nucleic acid) synthesis.
Initiator Peptide Workstation was developed to address the needs of peptide chemists and organic chemists synthesising peptides and peptidomimetics, including difficult post-synthetic modification of sequences using microwave irradiation.