TTP Labtech has added a 561nm laser to its high-content, microplate imaging system, the Acumen eX3, enabling it to perform additional high-throughput cell-based assays.
This new addition enables the use of a new range of dyes to increase the multiplexing capabilities of the machine.
Engineered to maximise imaging efficiency, without sacrificing quality, this platform collects and analyses more than 40 images per second, at a resolution equivalent to a 20x objective lens.
Due to its ability to rapidly scan the entire well area, the Acumen eX3 has recently been used for the analysis of colony-forming units from bone marrow and stem-cell cultures, and neutrophil adhesion assays.
The Acumen eX3 is said to be the only high-content cell-based screening system capable of performing simultaneous screening and data analysis, providing read times from as fast as six minutes for 24 to 3,456 well plates.
The Acumen eX3 imaging platform preserves the integrity of the assay and is effective for the analysis of both single cellular targets and multiple intracellular components.
Furthermore, the high-throughput capabilities of this system make it suitable for analysing image data from large-scale experiments, including RNAi screening.
The Acumen eX3 provides a system to rapidly analyse and process images from any high-content screening application.