ProImmune has launched Proarray Ultra, an array that allows analysis of more than 30,000 peptides or proteins at once and is claimed to be more sensitive than optimised ECL ELISA.
Typically requiring only 1ul of analyte sample, Proarray Ultra is designed to overcome the traditional trade-off between optimised 96-well plate-based assays, which are reliable and have good performance characteristics but lack the required throughput, and high-throughput array technologies, which are typically only semi-quantitative.
Flexible design parameters can accommodate thousands of peptides and proteins on an array for initial-exploration high-throughput screening, and then multiple replicates of validated markers for small-scale analytical characterisation later in the programme.
Provided to customers as a turnkey service, analysis with Proarray Ultra is claimed to enable a broad range of research programs that are, in many cases, unfeasible with existing approaches.
Applications include antigen and monoclonal antibody characterisation; analysis of serum antibody specificity; correlation of antibody responses with disease onset; progression and outcome; protein-protein interaction site mapping; iterative peptide and protein design; and general bioassay design.
