Softgenetics has released the latest version of its Mutation Surveyor software, which is designed for the analysis of DNA variants from Sanger sequence reads.
The new software, suitable for both research and clinical applications, incorporates multi-step alignment technology that reduces false-positive rates as well as being able to process noisy data.
In addition, the single analysis batch capability has been increased from its former limit of 400 sequence traces to 2,000 sequence traces per analysis on a 32-bit desktop Windows computer.
Version 4.0 now accepts mitochondrial forensic nomenclatures of Indels; includes Exon information in GBK references files; reports accession numbers; aligns sequences across circular genomes; and allows the creation, saving and exporting of custom Genbank references.
Kevin LeVan, product manager, said: 'In addition to breaking the base call into smaller seeds during the alignment process, the software employs a Mexican Hat wavelet to detect broadened peaks often miscalled or non-called by the base caller.
'These two new technologies allow for deeper analysis of "noisy" data segments, as well as a considerably more robust alignment, reducing the false-positive rate and increasing analysis accuracy,' he added.
The company is offering 30-day trials and no-cost web-based training on its genetic analysis software packages.
