Waters and Nonlinear Dynamics are combining their expertise to advance proteomics and metabolomics research.
Waters and Nonlinear Dynamics are to co-develop an analytical solution that derives information from complex data sets generated by large-scale proteomics and metabolomics experiments.
The companies collaborated on the development of the Waters Omics Research Platform with TransOmics Informatics first introduced in May during the ASMS Conference on Mass Spectrometry and Allied Topics in Vancouver.
The technology combined both Waters SYNAPT G2-S HDMS and TransOmics Informatics developed by Nonlinear Dynamics’ under an exclusive worldwide OEM agreement.
Waters first introduced ion mobility to mass spectrometry with the introduction of the SYNAPT High Definition Mass Spectrometer in 2007.
Used in small molecule research, protein characterisation, metabolite identification and bio-pharmaceutical applications, the Synapt HDMS system is the only mass spectrometer to employ high efficiency ion-mobility based measurements and separations to enable the analysis of sample ions differentiated by size, shape and charge as well as mass.
The added dimension of shape-selective separation increases the analytical specificity and sample definition so that scientists can extract more information from their samples, including the detection of components previously unseen by conventional mass spectrometers.
“The complexity of biological samples is so great that the sensitivity and specificity of analytical techniques required for biological discovery presents scientists with significant challenges when it comes to managing experimental data,” said James Langridge, Ph.D., Director of Pharmaceutical & Life Sciences Discovery, Waters Division.
Waters intends to commence shipments of its UPLC/SYNAPT G2-S HDMS-based instrument solutions with TransOmics Informatics during the fourth quarter of 2012.