The Möbius makes electrophoretic mobility measurements of macromolecules under dilute conditions.
The Möbius was designed with the goal of measuring the mobility and the hydrodynamic radius of precious protein samples, without perturbing these fragile species.
By overcoming the challenges presented by these delicate nanoparticles, the technological advancements embodied in the Möbius offer unique capabilities for traditional applications.
Electrical charge is a fundamental property of all macromolecules. In colloidal suspensions, the formulation stability depends critically on the amount of charge developed at the interfaces between particles and their solvent.
For most biomolecules — like proteins — electrostatic interactions exercise a profound influence on their conformation, function, and efficacy.
Practically speaking, electrophoretic mobility has been the most popular and widely accepted proxy for the molecular charge and interfacial potential, also known as the zeta potential.