The Calypso 2 measures macromolecular interactions of both specific and non-specific strains in proteins.
The system is based on a static light scattering system and automated measurements can be achieved without tagging, immobilisation or sample modifications.
Wyatt states that its composition gradient multi-angle static light scattering (CG-MALS) platform is able to characterise both specific and non-specific solute-solute interactions across a broad range of strengths.
The technique automatically prepares and injects macromolecular samples into the systems light scattering detector, eliminating the possibility of human error.
Depending on molar mass and buffer conditions, the Calypso system can probe concentrations from less than 1 ?g/mL to over 100 mg/mL c.
The Calypso consists of hardware and software to carry out its CG-MALS operations and is capable of working in conjunction with any Wyatt MALS instrument.
Wyatt has also announced a case study entitled ‘Light scattering for the masses’ which details the Calypso’s ability to create and deliver composition gradients to an online UV/Vis concentration detector.
To read the application note, please click on the link above.
