3D cell culture specialist Amsbio has announced the launch of a 384-well version of its AlvetexScaffold cell culture plates.
The AlvetexScaffold 3D cell culture plates provide biopharmaceutical companies with a tool to improve the predictive accuracy, productivity and biological relevance of their cell based high throughput testing.
“We are excited about extending the application of 3D cell culture to high throughput laboratories and groups who need to test larger numbers of parameters with cells in a 3D environment,” said Alex Sim, president of Amsbio.
A typical application for this new product is in cancer cell cytotoxicity testing. The 384-well plates allow scientists to grow tumour cells in a way that better mimics the way these cells grow in vivo.
It is then possible to test the cytotoxic effect of novel or existing anti-cancer compounds using standard cell health assays such as MTT, XTT, extracellular oxygen consumption and many others.
Researchers can then retrieve RNA and protein from the drug treated cells to study mechanism of action and look for biomarkers.
Additionally, AlvetexScaffold is also available in other formats including a 12-well culture plate, 24-well culture plate, 96 well plate, 6-well and 12-well inserts. These formats enable scientists to construct different 3D cell culture models and assays.
