Rapid drying with no loss of sample and no cross-contamination due to bumping is promised by a system for use with centrifugal solvent evaporators
Genevac has announced a new anti-bumping system, called Dri-Pure, for use in its popular centrifugal solvent evaporators.
Dri-Pure works by carefully controlling the reducing pressure in the evaporation chamber in combination with an increase in rotor speed to achieve greater g-force.
As the pressure drops, the unwanted solvent begins to boil off.
Under normal conditions, bumping of the solvent may be expected to occur, this effect may be curbed by spinning the samples at around 300g.
However, Genevac and their customers have identified a more complex effect with solvent mixtures, for example from HPLC fractions, and with certain pure solvents that have strong interactions with the solute.
To dry these more difficult samples without bumping requires sophisticated control of the pressure ramp, while increasing the applied g-force to around 450g.
In addition, heat flow to the samples must be reduced by switching off the infra-red heat lamps during the pressure ramping stage.
Dri-Pure achieves all this in embedded instrument software that makes such an elegant solution very easy to apply.
Dri-Pure therefore leads to rapid drying with no loss of sample and no cross-contamination due to bumping.
The patented Dri-Pure technology is now available for all current models of Genevac centrifugal evaporators, from the affordable DD-4 bench-top unit to the production-scale Mega 1200.
Genevac's technical director, Duncan Guthrie, commented: "Dri-pure offers significant benefits to our customers, especially those working in synthesis and purification.
Where other methods of solvent removal are either very laborious or lead to unacceptable cross-contamination, Dri-Pure running on a Genevac evaporator gives smooth, controlled solvent removal in optimum time.
It represents a significant benefit for chemists working in parallel synthesis, drug discovery and compound purification." The system will be demonstrated at the forthcoming Analytica and Drug Discovery shows in Europe as well as at Pittcon and ACS Spring Meeting in the USA.
