Polymer Laboratories has announced an exclusive licence with Aventis Pharma to manufacture, use, and sell tetrafluorophenol derivatised resin, used in combinatorial synthesis, worldwide
The licensed product will be marketed exclusively as PL-TFP resin from PL, as an addition to Polymer Laboratories's StratoSpheres product line.
PL manufactures the StratoSpheres range of highest quality resins for combinatorial and medicinal chemistry and peptide synthesis, which includes conventional microporous solid phase synthesis supports, high load scavenger resins and macroporous supports with rapid mass transfer.
PL-TFP resin is a microporous high load 1.4mmol/g resin with a 150-300µm (50-100 mesh) particle size.
PL-TFP resin is ideal for producing polymer-bound equivalents of Pfp esters.
These solid supported activated acids and sulphonyl chlorides can then be used to build amide and sulphonamide analogue libraries by reaction with amines.
PL manufactures polymeric supports under ISO 9001 to accommodate the largest batch requirements of bulk solid phase peptide synthesis and medicinal and combinatorial chemistry in quantities from 100g to 100kg and beyond in its purpose-designed facility.
The company manufactures polymeric particles in sizes from <1µm to >500µm for a wide range of pharmaceutical and clinical/diagnostic applications.
