Can be used to optimise the best combination of catalyst, reagent and solvents for synthesis and evaluate the effects of changing temperature and reagent concentrations on yield and purity
The Metz Syn10 from Radleys Discovery Technologies is said to offer truly versatile parallel synthesis with variable heating, cooling, refluxing and stirring.
The Metz Syn10 will simultaneously carry out ten reactions, each with a different temperature, from -30C to +150C.
Compact, simple to operate, and easily integrated into robotic systems, the Metz Syn10 is the perfect parallel synthesis system for both medicinal and process chemists looking for faster process development and reaction optimisation, says Radleys Discovery Technologies.
Designed for use in all types of process optimisation, parallel synthesis, chemical and catalyst development, the Metz Syn10 can be used to optimise the best combination of catalyst, reagent and solvents for synthesis and evaluate the effects of changing temperature and reagent concentrations on yield and purity.
The versatile system can also be used to optimise reaction times in an automated fashion as well as defining alternative synthetic routes for compound development.
The Metz Syn10 offers stirring control from 250rpm to 1200rpm, with a maximum temperature difference between any two adjacent wells of 180C.
Superior chemical resistance, gas tight sealing and easy operation are provided through proprietary PTFE capped tubes, which feature an all PTFE valve.
A central inlet/outlet manifold, combined with the gas tight PTFE caps allows the introduction of inert gas for air or moisture sensitive reactions.
An optional removable water-cooled reflux unit may be used to provide even and efficient refluxing within the glass reaction tubes, minimising solvent evaporation during synthesis for even highly volatile solvents.
Complementing the hardware, Metz Syn10 PC software provides a comprehensive suite of control options including individual well programming and profiling, controlled heating/cooling ramps, crash cooling function for rapid temperature changes, plus an on-the-fly function for modifying profiles in progress, multi-user feature, data collection and control by solution temperature.