Experimental work on column technology has highlighted the conditions under which silica-based columns may be used at high temperature, opening up TPLC use in modern labs
Temperature programmed liquid chromatography (TPLC) specialist Selerity Technologies has concluded a collaborative agreement with Restek.
The companies will work closely together to develop and market a new generation of silica columns for high performance liquid chromatography (HPLC) separations.
To date, temperature control has been overlooked as a key variable and physical parameter affecting separation.
The arguments against utilising temperature as an optimisation tool in chromatographic runs have traditionally concentrated on the poor temperature stability of silica-based columns and the lack of an adequate column heating system coupled with a mobile phase pre-heater. Selerity's research and development team has worked extensively on developing unique bonding chemistries to strengthen silica particles against hydrolytic breakdown in extreme reversed phase and high pH conditions.
This experimental work on column technology has highlighted the conditions under which silica-based columns may be used at high temperature, thereby opening up further acceptance of TPLC as a technique in the modern laboratory.
Selerity will benefit from Restek's expertise in the manufacture of silica columns.
Restek bonds a wide range of conventional and unique stationary phases to four distinct silica materials and provides these packings in standard, microbore, semipreparative, and preparative scale formats.
It alsos synthesises two silicas, Pinnacle DB and Pinnacle II, to control quality and reproducibility from raw materials to finished columns.
Brian Jones, VP production and technology development, Selerity Technologies, states: "Restek, with its unsurpassed customer service, excellent quality assurance, and solid foundation in HPLC, is an ideal partner for Selerity Technologies.
"We look forward to working together to introduce a new generation of highly stable silica-based columns into the HPLC market".
Becky Wittrig, HPLC product manager, Restek, says: "We are eager to extend our HPLC product line.
"We are confident that our collaboration with Selerity Technologies will deliver the most innovative column technology commercially available thereby meeting our customers expectations."
