Surface plasmon resonance module provides high-end research laboratories with high sensitivity, high dynamic range, fast measurement time and significant technological and cost advantages
Thermo Electron introduces the new surface plasmon resonance module, SPR 100, specifically designed for use with Thermo's FT-IR spectrometers, including the Nicolet x700 series, Nexus series and Magna-IR series.
The company says this module provides life science, pharmaceutical and food science research laboratories with high sensitivity, high dynamic range, fast measurement time and significant technological and cost advantages over existing SPR technology.
The module will be launched at the 3rd International Conference on Vibrational Spectroscopy of Monolayer Films (VSM) in Quebec, Canada.
The SPR 100 module enables the quantitative characterisation of many different types of biomolecular interactions including those involving DNA, RNA, protein, and carbohydrates in real time without the use of molecular labels, thereby decreasing measurement time and enhancing identification with increased sensitivity.
FT-SPR measures the wavenumber corresponding to the minimum reflectivity, resulting in significant sensitivity advantages over the traditional angle-shift based SPR technology.
SPR arises when light is reflected under certain conditions from a conduction film at the interface between two media of different refractive indices.
SPR causes a reduction in the intensity of reflected light at a specific angle, or specific wavelength (wavenumber) with respect to a conducting film surface.
This angle or specific wavelength varies with the refractive index close to the surface on the side opposite from the reflected light.
SPR reflectivity measurements are surface-sensitive spectroscopic methods used to characterize thickness and refractive index of chemical and biomolecular films on metal surfaces.