Experimental cancer research now incorporates direct injection of plasmid DNA into a tumour lesion, followed by electroporation to enhance the uptake of the plasmid DNA into tumour cells
BTX has introduced the ECM 830 square wave electroporation system and specialty electrodes.
Electroporation technology enhances cellular uptake of various molecules.
Experimental cancer research now incorporates a direct injection of plasmid DNA into a tumour lesion, followed by electroporation.
The localised electrical charge enhances the uptake of the plasmid DNA into tumour cells.
The plasmid DNA then stimulates cells within the tumour to produce high levels of a specific protein which in turn stimulates the immune system to generate antibodies against the tumour cells.
The BTX ECM 830 is specifically designed for mammalian cell and in vitro electroporation.
The two-needle array electrodes are just one example of specialty electrodes used for in vivo gene and drug delivery.
Additional electrodes available include the Tweezertrode, Genetrode and Calliper electrodes.
The BTX global technical support team will assist scientists worldwide to optimise their applications and choose the best accessories for their applications.
