ProteinCenter integrates the contents of a large number of public protein sequence databases, experimental systems biology data, a number of bioinformatics tools and much more
ProteinCenter integrates the contents of a large number of public protein sequence databases, experimental systems biology data, a number of bioinformatics tools and much more to be a most comprehensive bioinformatics analysis tool and a must-have for any scientist who looks at protein and sequence information.
Much more efficient functional analysis.
Data mining and categorizing of large data sets (100s or 1000s of proteins).
Comparisons of lists of proteins which take into account all the differences arising from allelic, splice variant or splicing variations as well dealing with fragment vs full length and all this independent of accessions numbers.
Integration of public sequence databases to form a comprehensive and consistent super-set.
Includes e.g GenBank, Refseq, EMBL, UniProt, Swiss-Prot, Trembl, PIR, IPI, PDB, Ensembl etc.
The super-set is consistent over time and retired data records are tracked (this accounts for many thousands of protein identifier each year).
Clustering of sequences.
The sequence similarity is pre-computed for all sequence records.
Looking at large data sets, it greatly reduces complexity to see protein families collapsed rather than represented as many different proteins (by name or ID).
Comparison of large data sets of proteins.
Comparisons of data sets independent of original source (eg, IPI vs UniProt).
Full control of alleles, splice variants, fragments and full length sequences.
Eg,fragments in one sample may be recognized as the same proteins as the full length in another sample.
Computational Enrichment of the sequence data.
A range of biologically relevant sequence features are pre-computed and stored in the database for easy filtering/querying and sorting of data.
Eg, the presence of signal peptide and trans-membrane sequences is stored.
Algorithms in ProteinCenter provide much more annotations than the existing annotation in the public databases.
Pre-computed annotations are integrated with consolidated annotation from public databases.
ProteinCenter has a very deep protein sequence integration allowing a number of analysis features not found in other bioinformatics software.
Other features include easy creation of summary statistics and reports.
Categorizing of large data sets by filtering.
Workspace for storage of data sets.
Lookup of accession codes and peptides.
Instant Blast with rich annotation.
