Shimadzu Biotech enhances bio-research analyses with its new Axima-Tof2 high-energy Maldi CID MS/MS instrument delivering greater sensitivity and flexibility
Shimadzu Biotech has introduced the Axima-Tof2, its new high-performance Maldi Tof-Tof mass spectrometer.
Representing the next generation in high-energy collision induced dissociation (CID) MS/MS instrumentation, the Axima-Tof2 brings enhanced flexibility to life science laboratories, significantly extending the type of analyses they can provide.
The device was introduced at the 54th American Society for Mass Spectrometry Conference in Seattle.
With Shimadzu Biotech's intuitive software bundled as standard, the Axima-Tof2 is said to be ideal for use in open-access lab environments, delivering maximum results while requiring the minimum in user input.
As a result, the system is equally robust and reliable whether employed by novices, or expert users, while the inclusion of industry standard XML data exporting allows it to integrate easily and seamlessly into any workflow.
Beyond its use in proteomics, the Axima-Tof2 is equally adept at analyzing and processing polymers, oligonucleotides, SNPs, metabolites, lipids, carbohydrates and small molecules.
Using high-energy CID to augment fragmentation of analytes, Shimadzu Biotech's Axima-Tof2 mass spectrometer maximises its curved field reflectron technology to deliver MS/MS data without the need for post-acceleration.
"The Axima-Tof2 high-energy CID is an invaluable system for a multitude of applications, ranging from protein identification to de novo sequencing," noted Emmanuel Raptakis, product manager for Shimadzu Biotech.
"In fact, analysis of a wide variety of compound classes, like lipids and carbohydrates, is already yielding invaluable structural information previously out of reach for lower energy MS/MS approaches".
The novel ion gating technology employed in the Axima-Tof2 affords industry-leading precursor ion isolation resolution, which allows the successful MS/MS analysis of the most challenging complex mixtures.
The curved field reflectron technology, under licence from Johns Hopkins University, MD, US, has been updated to enhance the sensitivity and quality of high energy CID MS/MS.
Ion scattering is minimised by utilising a totally grid-less ion path and helium as the collision gas of choice.
