Chromatrap offers an optimised buffer chemistry for the isolation of high quality and high yield chromatin.
The success of any ChIP assay is dependent upon the quality of the chromatin. The buffer system for chromatin extraction developed by Chromatrap has been cited in a growing number of recent publications (see https://www.chromatrap.com/publications/) including investigations into G-quadruplex structures in human regulatory chromatin and receptor signals in natural killer cells.
Chromatrap has optimised products to enable users to prepare chromatin using mechanical fragmentation (sonication) or enzymatic digestion. Offering both types of extraction kit gives the flexibility of applying different methods according to particular research needs. The conmpany's sonication shearing kit and enzymatic shearing kit contain buffers for up to ten chromatin preparations and guarantee the best quality chromatin from samples.