Offering complete disruption of cytoplasmic and nuclear membranes, Porvair Sciences’ Chromatrap buffer chemistries are optimised for sonication and enzymatic shearing.
The lysis and hypotonic buffers are high performance reagents for the critical first step of isolating chromatin from a sample. For enzymatic shearing from fixed cells or tissue , the detergent-based buffers are suitable for effective fragmentation of nuclear material.
For the disruption of cell membranes, the optimised hypotonic buffer composition ensures effective lysis of cell membranes to aid in the release of nuclei material from a wide range of varied species.
Formulated for difficult to lyse cell types and tissues, the optimised lysis buffer is proven to enable researchers to better explore and understand the underlying processes and mechanisms that drive biological organisms.
For further information on Chromatrap lysis and hypotonic sonication buffers please visit https://www.chromatrap.com/lysis-buffer-for-enzymatic-shearing/ or contact Porvair Sciences Ltd on +44 1978 666222 / +1 856 696 3605 / support@chromatrap.com.
