Dr. Fernando Ferrer, senior scientist at the prestigious p53 Laboratory of the Agency for Science, Technology and Research in Singapore has extolled the effectiveness of CEM’s Liberty Blue Peptide Synthesiser, and he should know, because their lab has just bought a second system.
Dr. Ferrer has a remarkable track record in peptide chemistry. Having worked at The Burnham Institute in La Jolla, Amylin Pharmacuticals, and now in Prof Sir David Lane’s p53 lab, he has been actively involved in using microwave technology for solid-phase peptide synthesis for over ten years.
In the p53 lag, in collaboration with Professor Greg Verdine of Harvard University, Dr Ferrer is now working to develop and research the capabilities of stapled peptides in the p53 pathway. The p53 peptide acts as a tumour suppresser in many tumour types by inducing growth arrest or apoptosis. P53 is also involved in cell cycle regulation as a transactivator that negatively regulates cell division. This is medically very importantresearch, as defects in p53 are the cause of numerous cancers.
Dr Ferrer’s work therefore requires a peptide synthesis system that offers flexibility, efficiency and reliability, which is why he has repeatedly turned to CEM’s Liberty Blue automated microwave peptide synthesiser. Such has been the Liberty Blue’s success in assisting the lab’s production of their benchmark peptides, including the synthesis of stapled peptide VIP116, and their new Pepcohol resins (patent pending), that they have now purchased a second system.
As Dr. Fernando Ferrer concludes, “The Liberty Blue is one of the best peptide synthesisers available in the market, facilitating the research in peptide chemistry and life sciences.” Further details can be found on CEM’s website.
