Nonoparticle Size And Concentration With Videodrop
12 Jul 2021
Videodrop, a device designed to measure the size and concentration of nanoparticles in a single drop in real time, is now available through Meritics.
Based on the works of the Langevin Institute, a French academic laboratory specialised in optical and ultrasonic technologies for life sciences, Videodrop relies on a single-arm interferometric technique. This makes it possible to visualise living nanoparticles such as viruses, phages, or extracellular vesicles.
In a simple process, a solution of 5 to 10µL containing nanoparticles is placed on a microwell lit by a simple LED, while an optic system, coupled to a camera, films their movements. The device films in real time all the particles of between 10 nm and 10µm in a drop. No labelling is necessary on the analysed sample without purification and on small volumes (5µL) with a concentration range of 10^8 to 1011particles/ml.
The resulting movie shows in real time the displacement of the nanoparticles. A tracking algorithm allows users to follow the trajectory of the observed objects. Dedicated software calculates the speed and trajectories to help define the type, the size, and the number of observed elements. The result is displayed on the user’s interface almost instantly.
For more information on Videodrop, contact Meritics here.