Sartorius has published a free eBook exploring some of the latest developments in the field of antibody development and highlighting key methodologies used to evaluate novel antibodies across a range of disease areas.
Evolution of monoclonal antibodies (mAbs) has resulted in the next generation of antibody therapeutics, engineered to enhance characteristics such as target cell killing potency. These include antibody–drug conjugates (ADCs), bispecific antibodies, engineered antibodies, antibody fragments, and nanobodies.
It is important to have robust, high-throughput methods to screen antibody libraries to keep up with the broad and ever-changing disease landscape. To discover effective treatments for rare diseases or against poorly expressed targets, it may be necessary to screen antibody binding, and functional capacity across huge hybridoma or phage display libraries.
Targeted at researchers including those working in immuno-oncology, virology, neuroscientists and cancer immunotherapy drug discovery researchers, biotechnology, pharmaceuticals, biopharma, research institutes and academia, the eBook includes valuable notes on screening antibody libraries and an interview with Dana Duey, one of the leading lights of antibody discovery.
Access the eBook here.
