Radleys recently held a meeting at Duxford Air Museum, UK, with users and researchers interested to learn more about the Lara controlled laboratory reactor and Coflux calorimetry system
This inaugural meeting was organised to provide a forum for researchers in pharmaceutical and chemical process development to hear how Lara and Coflux are being implemented to save time, space and perform chemistry more efficiently, to enable cross-fertilisation of ideas, to discuss new developments and to allow users to pose technical questions.
Among the 47 people present there were representatives from companies including Agfa-Gevaert, Almac, AWE, Carbon Trust, Croda Universal, Genzyme, GlaxoSmithKline, Helsinn Chemicals, Novartis, Pfizer, Pharmamorphix, Powder Systems, Rhodia, Santaris Pharma, Solutia UK, Spirogen, Syngenta, SynProtec, the London School of Pharmacy, UCB Celltech, Vernalis and William Blythe.
Chris Hughes of GSK gave an illustrated talk describing how Lara CLR systems were positively impacting pharmaceutical process development within his company and were now the main workhorse for specialist studies.
David Dale of Pfizer presented another well-received talk on his company's participation in the development of the Coflux calorimetry system.
The rapid set-up and calibration-free operation of the Coflux system generated a lot of discussion of how the technique will save time, and provide valuable real time enthalpy data for enhancing process safety, controlling crystallisation studies, improving end-point detection and in combination with other process analytical techniques provide a rapid process development tool.
Overall the symposium generated a considerable amount of enthusiastic discussion.
Other seminars covered a range of topics including: An introduction to the design principles of Lara ; An introduction to Calorimetry ; Using Coflux for Development and Scale up of processes and the Future of Lara and Coflux.
