Based on the industry standard Microlute design, the protein precipitation plate, p3, from Porvair Sciences uses the Crash method allowing 96 samples to be handled simultaneously
Biological samples commonly contain proteins that interfere with downstream applications.
As the number of biological samples has increased so has the need for a high throughput approach to remove these proteins.
Based on the industry standard Microlute design, the protein precipitation plate, p3, from Porvair Sciences uses the Crash method allowing 96 samples to be handled simultaneously.
The p3 uses the Crash method wherein samples are treated with acetonitrile to denature the protein that is then filtered out.
Protein precipitation happens in situ in the wells and the p3 solves all common problems with the traditional methodology.
Incorporating a novel treated dual frit matrix the p3 eliminates wetting-out and leaking of sample through the plate before the application of vacuum.
The novel treated frit matrix also maintains high flow rates enabling quick sample preparation times.
The p3 plate has been tested in independent tests and shown not to have any major adverse non-specific binding problems and is the protein precipitation plate of choice for a growing number of major pharmaceutical companies.
Adopting the footprint of a standard 96-well plate the p3 is readily integrated into automated systems offering the possibility of further productivity gains.
