CLC Bio has released molecular diagnostics for Multilocus Sequence Typing (MLST), a portable and precise state-of-the-art technique for typing bacteria and yeast isolates
The development of this new module was motivated by usability studies showing that a typical current-day MLST workflow takes 25 minutes on average.
Now, with CLC bio's MLST Module, scientists can conclude the same work in less than a minute and with only a few clicks of the mouse.
Research scientist DVM, Evert Jor, from the National Veterinary Institute in Oslo, Norway, states: "Previously, the lack of adequate and professional software has been a major obstacle for establishing a single, integrated MLST analysis workflow.
"With this software from CLC bio, we can entirely eliminate the old tedious workflows".
A typical MLST workflow includes assembly, inspection of assembly, trimming of sequence ends, copying and pasting into a web form, and noting the allele number.
This routine must be repeated for all loci, leaving room for manual errors and scarce time for inspection of the results.
On average, this non-integrated workflow takes 25 minutes - a process which CLC MLST Module can achieve in under a minute and with a couple of clicks of the mouse.
Moreover, the user can easily inspect and edit the sequencing data to correct sequencing errors and verify the result, thereby delivering higher quality results in considerably less time.
Senior scientific officer at CLC Bio, Roald Forsberg, states: "As the amount and complexity of data within molecular diagnostics continually increases, so does the demand for optimised bioinformatics solutions.
"We believe that nucleotide-based microbial identification and typing is the future, and that is why CLC MSLT Module is only the first in a line of molecular diagnostics solutions from CLC bio".
