HuCAL technology is revolutionising the way monoclonal antibodies are generated and offers advantages over traditional animal-based methods - including speed, specificity and production technology
This valuable 84-page publication describes the principles behind HuCAL recombinant antibodies, the basis of their exceptional specificity and presents protocols, examples and troubleshooting tips for their use in applications such as Western blotting, Elisa, IHC, IP and flow cytometry.
A free copy is available from AbD Serotec.
HuCAL antibodies are selected from a high quality, synthetic library of more than 15 billion expressible antibody specificities.
This is the very latest and most powerful library created by MorphoSys and has already generated thousands of monoclonals for researchers worldwide.
In addition to explaining the key design and construction features of the HuCAL library, the technical manual also explains why HuCAL antibodies are preferable to full IgGs for IHC, cell isolation and even protein crystallisation; how the selection can be geared to directly generate a monoclonal antibody that can distinguish between a wild-type protein and a single amino acid mutation; and why using the AgX antigen expression service can lead to increased specificity and functionality for your antibodies.
